A 2018 study has found that taking LactoSpore® Bacillus coagulans (found in Nutrafruit’s Queen Garnet Probiotic & Prebiotic) daily significantly reduces clinical symptoms of IBS. In our previous blog post we also discussed other findings from the study including helping depression, sleeplessness and decreasing signs of inflammation.
What is IBS?
IBS, or Irritable Bowel Syndrome, is an intestinal condition that can result in constipation, diarrhoea, cramps, pain, bloating, gas and food sensitivities. This can be particularly debilitating for patients as their discomfort can lead to embarrassment, isolation and anxiety. It can seriously impede one’s quality of life
Participants were instructed to take either LactoSpore® or a placebo every morning for 90 days.
Researchers used questionnaires/scales to determine the effectiveness of the probiotic.
All primary measures of effectiveness for the LactoSpore® group were statistically significant on day 60 and this was maintained until the study ended. Measures included the positive changes in:
- Irritable Bowel Syndrome Quality of Life questionnaire (34 questions surrounding helplessness, embarrassment, vulnerability, sense of control, enjoyment in life, depression, isolation, irritation, fear, cleanliness, eating habits, anxiety/worry, productivity)
The following secondary efficacy parameters were also found to be statistically significant for the LactoSpore® group:
- Clinical Global Impression-Improvement (scale from very much improved to very much worse) and Severity Rating Scales (scale from normal to severely ill)
- Gastrointestinal Discomfort Questionnaire
Researchers also analysed serum myeloperoxidase, an inflammatory biomarker, before and after the trial:
- Significantly reduced in the LactoSpore® group but not placebo group. Inflammation is the culprit behind a multitude of health issues such as diabetes, Alzheimer’s, arthritis, heart disease and IBD.
 A biomarker is a measurable indicator of a biological process (e.g. there are indicators of inflammation that c
Read our previous blog post here to read how the researchers found a decrease in symptoms of depression, sleeplessness and inflammation.